4 курс / Акушерство и гинекология / Практическая_кольпоскопия_Роговская_С_И_
.pdf
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1991 .). . 5 -
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, Lactobacillus spp., Staphylococcus epidermidis, Streptococcus spp., Peptostreptococcus spp., Eubacterium spp.
Micrococcus spp., Propionibacterium spp., Bacteroides spp., Ureaplasma urealiticum,
.
Clostridium spp., Candida spp., Gardnerella vaginalis, Bifidobacterium spp., Micoplasma hominis, Actinomyces spp., .
, Escherichia coli, Staphylococcus aureus, Neisseria spp., Mycoplasma fermentans.
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[3, 12, 25].
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(CIN 1, II, III),
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3.1.
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[34, 35].
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) .
1. HSIL [57]
|
|
, |
, |
|
|
% |
% |
|
|
|
|
Reid R. (1991) |
1012 |
52,0 |
92,0 |
|
|
|
|
Soost H.J. (1991) |
277 842 |
78,1 |
94,4 |
|
|
|
|
Tabarra S. (1992) |
75 |
66,0 |
82,0 |
|
|
|
|
Echini (1993) |
2105 |
62,5 |
99,3 |
|
|
|
|
Mayeaux J. (1995) |
453 |
45,0 |
80,0 |
|
|
|
|
Schneider A. (1996) |
967 |
28,9 |
97,5 |
|
|
|
|
Malsuura Y. (1996) |
151 |
51,0 |
95,0 |
|
|
|
|
Bishop J.W. (1997) |
2320 |
63,6 |
99,7 |
|
|
|
|
.(2001) |
210 |
64-74 |
77-89 |
|
|
|
|
Petry K.U. (2003) |
8466 |
46,0 |
98,0 |
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: , ( ) ASCUS ( . 2 ) ( )
(LSIL) ( 2 ) (HSIL) ( . 2 ) .
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2. , 2001 (Terminology Bethesda System (TBS) [44]
AGC |
Atypical glandular cells |
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AGC, favor |
Atypical glandular cells, favor |
, |
neoplastic |
neoplastic |
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ASC |
Atypical squamous cells |
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ASCUS |
Atypical squamous cells |
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|
undertermined significance |
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ASCH |
Atypical squamous cells cannot |
, |
|
exclude HSIL |
HSIL |
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|
CIN 1, II, III |
Cervical intraepithelial neoplasia |
1, 2 |
|
grade 1, 2 or 3 |
3- |
|
|
|
CIS |
Carcinoma in situ |
in situ |
|
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|
HSIL |
High grade |
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|
squamous intraepithelial lesion |
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. 2 |
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LSIL |
Low grade |
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|
squamous intraepithelial lesion |
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NOS |
Not otherwise specified |
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SIL |
Squamous intraepithelial lesion |
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( )
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. 2001 :
» « » [33].
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8000—12 000
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ASCUS
(HSIL).
CIN II CIN III [44, 110].
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(ASCUS), -
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( . 3) [93, 120].
3.
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(Bethesda system) |
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1 |
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II |
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. 3 |
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(Papanicolau system) |
(Bethesda system) |
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Ilia |
ASCIIS ( ) |
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ASCH ( ) |
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• |
AGUS |
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• |
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1116 |
LSIL (CIN1) |
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HSIL (CIN 2) AGC |
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IV |
HSIL (CIN 3) AIS |
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V |
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[57].
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3.2.
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[23].
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[110, 189].
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.
[41, 93, 112].
:
— ( ; punch-byopsy);
- ( ; excisional biopsy) ( . 11).
(Cervicalpunch-biopsy)
'.
• ;