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11  Imaging of Postoperative Spine

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11.3.12  Interbody Fusion

11.3.12.1\ Discussion

The goal of lumbar interbody fusion with prosthetic devices is to provide stability while promoting bony ingrowth. Many materials and devices have been used for this purpose, including bone threaded bone graft dowels or femoral rings, metal cages, and polymer cages. Femoral ring grafts are cylindrically shaped and inserted into the intervertebral disc space via anterior lumbar interbody fusion, posterior lumbar interbody fusion, or transforaminal lumbar interbody fusion approach (Fig. 11.63). A major disadvantage of such allograft device is the risk of disease transmission. Wide varieties of metal cages have been and continue to be developed. The first-­generation Bagby and Kulich (BAK) and second-­generation Ray threaded fusion cages are cylindrical, hollow, porous, threaded, titanium alloy cages that can be screwed into position in the intervertebral disc space (Fig. 11.64). The more recent third-generation LT-CAGE has been widely used in North America and has a trapezoidal, tapered configuration that provides increased surface area for bone growth and facilitates restoration of lumbar lordosis (Fig. 11.65).

a

More recent interbody fusion devices are mainly composed of polyether ether ketone (PEEK) or biocompatible high-density carbon fiber. These materials are radiolucent, which facilitates visualization of the bone graft-­vertebral body endplate interface. The devices also contain press-fit titanium markers in order to demarcate the boundaries of the device on radiographs. Many designs are in use, but generally are rectangular with grooves in order to promote vertebral body attachment. There are a variety of approaches that can be used for interbody fusion (Figs. 11.66, 11.67, 11.68, 11.69, 11.70, and 11.71 and Table 11.2).

Imaging can be used to assess the position of the implants, which should be located at least 2 mm anterior to the posterior wall of the vertebral body. Another role of imaging following interbody fusion surgery is to assess fusion versus pseudarthrosis. Radiographs with lateral flexion and extension views can be used for this purpose, although the accuracy is highly dependent upon precise positioning and the type of implant. Rather, CT is the modality of choice for evaluating interbody fusion, although the streak artifact from the early stainless devices can obscure adjacent bone formation. Early bone healing can often be appreciated at 3 months and is usually nearly complete at 6 months after surgery.

b

Fig. 11.63  Femoral ring allograft. Axial (a) and coronal (b) CT images show a cylindrical bone fragment inserted into the intervertebral disc space (arrows)

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a

b

Fig. 11.64  Threaded cage. Sagittal (a) and coronal (b) CT images show two cylindrical hollow cages screwed into the intervertebral disc space

a

b

Fig. 11.65  Tapered LT-CAGE. Lateral radiograph (a) and sagittal CT image (b) show two metallic cages fitted into the intervertebral disc spaces. Mature bony fusion is most apparent on the CT

11  Imaging of Postoperative Spine

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a

b

Fig. 11.66  PLIF. Axial (a) and sagittal CT (b) images

intervertebral disc space. Laminectomy and posterior

show the radiolucent PEEK cage with metallic markers

fusion hardware is also present

and filled with bone graft (arrows) in the midline of the

 

a b

Fig. 11.67  TLIF. Axial CT (a) and axial T1-weighted (b) show the PEEK cage (arrows) positioned obliquely in the intervertebral space at nearly a 45° angle with respect to the sagittal plane

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a

b

c

Fig. 11.68  XLIF. Axial (a) and coronal (b) CT images show the metallic markers of the XLIF device, which is positioned in the intervertebral space. There is bone graft

material within the device. Axial T1-weighted (c) MRI shows the XLIF device as low signal intensity with a “figure of 8” shape

Fig. 11.69  ALIF. Lateral radiograph shows a Synfix device implanted in the L5–S1 anterior disc space (arrow). Posterior stabilization hardware is also present

11  Imaging of Postoperative Spine

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a

b

Fig. 11.70  Stalif. Frontal radiograph (a) and sagittal CT image (b) show that the device composed of both radiolucent and metallic parts, including titanium screws that

enter the anterior vertebrae above and below. Note the absence of additional hardware. As such, the device “stands alone”

Fig. 11.71  Transsacral fusion. Sagittal CT image shows the vertically oriented axial lumbar interbody fusion hardware and mature bony bridging across the L5–S1 disc space

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Table 11.2  Types of interbody fusion

 

 

 

 

 

 

Photographs of various types of

Device

Description

interbody fusion devices

PLIF (posterior lumbar

Consists of a posterior midline approach to the

 

interbody fusion)

disc space. The interbody cage is inserted into

 

 

the intervertebral disc space via a laminectomy

 

 

or hemilaminectomy defect. As a result, the

 

 

long axis of the device is typically positioned

 

 

nearly parallel to the sagittal plane. Concurrent

 

 

facetectomy is often performed

 

 

 

 

TLIF (transforaminal lumbar

Modification of the PLIF procedure, in which

 

interbody fusion)

the interbody fusion prosthesis is more lateral.

 

 

The long axis of the cage tends to be positioned

 

 

obliquely (approximately 45°) with respect to

 

 

the sagittal plane. This procedure can be

 

 

performed via a midline approach as a PLIF or

 

 

a minimally invasive approach with two

 

 

paramedian incisions. Full facetectomy

 

 

(unilateral or bilateral) is also performed.

 

 

Fixed-size or expandable cages can be inserted

 

 

into the disc space

 

XLIF (extreme lateral

Proprietary PEEK implant that is inserted

 

interbody fusion; NuVasive,

laterally into the intervertebral space through a

 

Inc., San Diego, CA)

minimally invasive retroperitoneal approach.

 

 

These implants have a characteristic of long,

 

 

rectangular shape, designed to maximize

 

 

surface area on which the epiphyseal ring can

 

 

rest. There are also slots for packing bone graft.

 

 

Other vendors endorse this approach and have

 

 

different variations on the lateral cage

 

OLIF (oblique lumbar

A variant on the XLIF where the lateral spine is

 

interbody fusion; Medtronic,

approached obliquely instead of orthogonally.

 

Minneapolis, MN)

The cages are placed in a similar fashion to the

 

 

XLIF technique

 

ALIF (anterior lumbar

Consists of anterior discectomy and insertion

 

interbody fusion)

of the interbody prosthesis via a retroperitoneal

 

 

approach. The procedure can be performed

 

 

with or without posterior stabilization.

 

 

However, the addition of pedicle screw fixation

 

 

with ALIF results in a significant increase in

 

 

the rate of interbody fusion

 

 

 

 

Stalif (stand-alone lumbar

Can absorb energy, handle the normal weight

 

interbody fusion)

of the body, and minimize stress on adjacent

 

 

levels. Thus, the devices do not require

 

 

additional fusion procedures, such as posterior

 

 

pedicle screw and rod fixation

 

AxiaLif (transsacral fusion)

Can be performed using the AxiaLif® system

Photograph of AxiaLif device.

 

(TranS1, Inc., Wilmington, NC). Initially, a

(Courtesy of Quandary Medical)

 

series of guide pins and dilator tubes are

 

 

inserted under fluoroscopic guidance and used

 

 

to obtain access to the L5–S1 disc space.

 

 

Subsequently, a discectomy is performed

 

 

percutaneously. Finally, a threaded titanium pin

 

 

is placed across the disc space. This procedure

 

 

is often combined with posterior fixation with

 

 

facet or pedicle screws introduced through a

 

 

minimally invasive technique